Connect with us

Recommended

Dr. Kevin Dalby Reveals Top 5 Advances in Modern Oncology

Published

on

Dr. Kevin Dalby

The field of oncology has progressed substantially over the last 50 years. As Dr. Kevin Dalby explains, these modern advances have led to breakthroughs in cancer prevention efforts, innovative therapies that target cancer cells, and clinical research.

Top five advances in modern oncology:

Here are the top five advances in modern oncology that have changed how the scientific world approaches cancer.

#1. HPV Vaccine

One of the most significant oncological developments of the last 20 years happened in 2006 when the vaccine for Human papillomavirus first became available. All HPV vaccines can protect against HPV types 18 and 16 at the very least.

Studies have found that the vaccine could prevent up to 80% of anal cancers, 70% of cervical cancers, 40% of vulvar cancers, and 60% of vaginal cancers.

Since the creation and approval of the HPV vaccines, the World Health Organization has made them part of their recommended routine vaccinations for every country.

#2. Discovery of the TP53 gene

In 1979, scientists discovered what has now known as “the guardian of the genome” — the TP53 gene. Sometimes called p53, the gene helps prevent cancer formation and helps conserve stability as it prevents mutations of genes.

The p53 protein it produces also helps suppress the growth of tumors and control the proliferation of cells. This gene is the one that mutates most frequently, making it key to help prevent mutations.

#3. MOPP

Nearly 60 years ago, in 1965, it was discovered that administering combination chemotherapy to patients induced remission over a long period for more than half of all adults who had Hodgkin lymphoma. The combined chemotherapy was called MOPP for mechlorethamine, vincristine, procarbazine, and prednisone.

Today, roughly 90% of patients with this type of cancer can be cured due to the discovery of MOPP.

#4. Anti-Nausea Drugs

In 1991, doctors introduced ondansetron, a powerful drug that calms nausea in chemotherapy and other treatments. This was a remarkable discovery and one that has made advanced cancer treatments much more doable for patients.

Beyond just making patients more comfortable, it helps them avoid going to the hospital regularly and allows them to complete the full treatment course, which results in better and longer lives.

#5. PLCO Cancer Screening

In 2012, it was discovered through clinical trials that screening of people who are at least 55 years old for colorectal cancer reduced both the number of cancer cases and mortality rates.

As Dr. Kevin Dalby explains, the trials found that screened individuals had a 21% lower risk of developing this type of cancer and a 26% lower risk of dying from it.

Today, screening for colon cancer is routine and commonplace for individuals over the age of 55. It’s even become a procedure used in younger individuals who may be at greater risk of colon cancer.

About Dr. Kevin Dalby

Dr. Kevin Dalby is a chemical biology and medicinal chemistry professor who is currently working on cancer drug discovery. At the College of Pharmacy at The University of Texas, he examines the mechanisms of nature and cancer to develop new treatments and teach and motivate students to conduct research. Dalby is optimistic about the future of cancer treatments.

 

I cover national business news and lifestyle for Metic Press. Previously, I've written for TIME, Newsweek, the New York Daily News and VICE News. I am also an editor at HuffPost, a small business news room for a young audience.

Continue Reading

Recommended

Maximizing Pharmacy Profitability Through Strategic Vendor Relationships

Published

on

Maximizing Pharmacy Profitability Through Strategic Vendor Relationships

In today’s competitive pharmacy landscape, the difference between thriving and merely surviving often comes down to how well you manage your vendor relationships. Strategic vendor partnerships can dramatically impact your bottom line, from securing better pricing to accessing innovative solutions that drive efficiency.

Understanding the Vendor Ecosystem

The Modern Pharmacy Vendor Landscape

Today’s pharmacies rely on multiple vendor relationships:

  • Primary wholesalers
  • Secondary suppliers
  • Technology providers
  • Equipment manufacturers
  • Professional service providers
  • Specialty medication distributors

Each relationship presents unique opportunities for optimization and cost savings.

Building Strategic Vendor Relationships

  1. Primary Wholesaler Optimization

Your primary wholesaler relationship is typically your most critical vendor partnership. Here’s how to maximize its value:

Contract Negotiation Strategies

  • Review historical purchase volumes to leverage buying power
  • Analyze generic compliance ratios for better pricing tiers
  • Negotiate payment terms that optimize cash flow
  • Secure better return goods policies
  • Include performance guarantees in contracts

Volume Commitment Optimization

  • Track monthly compliance to volume commitments
  • Understand the impact of brand vs. generic mix
  • Monitor contract tiers and thresholds
  • Plan seasonal buying strategies
  • Leverage special buying opportunities
  1. Secondary Supplier Management

Smart use of secondary suppliers or getting involved in the Canadian Pharmacy Partner program can significantly impact profitability:

When to Use Secondary Suppliers

  • Short-dated special buys
  • Stock shortages from primary wholesaler
  • Competitive pricing opportunities
  • Specialty item access
  • Emergency inventory needs

Risk Management

  • Verify supplier credentials
  • Monitor product authenticity
  • Track pricing variances
  • Maintain quality control
  • Document all transactions

Technology Partner Selection

Key Considerations

  • Integration capabilities with existing systems
  • Total cost of ownership
  • Training and support services
  • Upgrade paths and future scalability
  • Data security and compliance features

ROI Analysis

  • Implementation costs
  • Ongoing maintenance expenses
  • Productivity gains
  • Error reduction
  • Customer satisfaction improvements

Cost Optimization Strategies

  1. Inventory Management
  • Implement just-in-time ordering
  • Use data analytics for demand forecasting
  • Optimize par levels
  • Reduce expired product waste
  • Leverage seasonal buying opportunities
  1. Payment Terms Optimization
  • Negotiate early payment discounts
  • Balance cash flow requirements
  • Consider financing options
  • Track payment performance
  • Monitor rebate opportunities

Performance Measurement

Key Metrics to Track

  1. Financial Metrics
    • Purchase price variance
    • Payment term savings
    • Contract compliance rates
    • Return on investment
    • Total cost of ownership
  2. Operational Metrics
    • Order fill rates
    • Delivery performance
    • Quality metrics
    • Service levels
    • Response times

Vendor Relationship Management

Best Practices

  1. Regular Communication
    • Schedule quarterly business reviews
    • Maintain open dialogue
    • Share performance feedback
    • Discuss market trends
    • Plan future initiatives
  2. Documentation
    • Track all agreements
    • Monitor performance metrics
    • Document issue resolution
    • Maintain communication records
    • Keep compliance documentation

Innovative Partnership Models

Value-Added Services

  • Staff training programs
  • Market intelligence sharing
  • Technology solutions
  • Business consulting
  • Marketing support

Risk-Sharing Arrangements

  • Performance-based contracts
  • Shared savings programs
  • Joint venture opportunities
  • Collaborative initiatives
  • Innovation partnerships

Future-Proofing Vendor Relationships

Emerging Trends

  1. Digital Transformation
    • E-commerce integration
    • Automated ordering
    • Real-time analytics
    • Blockchain technology
    • AI-powered forecasting
  2. Sustainability Initiatives
    • Green packaging
    • Carbon footprint reduction
    • Waste minimization
    • Recycling programs
    • Environmental compliance

Crisis Management and Continuity Planning

Developing Backup Plans

  • Identify alternative suppliers
  • Maintain emergency contacts
  • Document contingency procedures
  • Test backup systems
  • Review insurance coverage

Risk Mitigation

  • Diversify supplier base
  • Monitor market conditions
  • Track supplier financial health
  • Maintain safety stock
  • Document quality issues

Conclusion: Creating Lasting Value

Successful vendor relationships require ongoing attention and strategic management. Key takeaways for maximizing profitability include:

  1. Strategic Focus
    • Align vendor relationships with business goals
    • Regularly review and optimize partnerships
    • Measure and track performance
    • Maintain clear communication
    • Plan for future needs
  2. Operational Excellence
    • Implement efficient processes
    • Leverage technology solutions
    • Monitor compliance
    • Maintain quality standards
    • Document everything
  3. Continuous Improvement
    • Regularly assess performance
    • Seek innovation opportunities
    • Adapt to market changes
    • Foster collaborative relationships
    • Share success metrics

By following these guidelines and regularly reviewing your vendor relationships, you can create sustainable competitive advantages and improve your pharmacy’s profitability. Remember that successful vendor relationships are partnerships, not just transactions, and require investment in time and resources to maximize their value.

 

Continue Reading

Recommended

6 Steps to Take Before Investing in Oil and Gas: A Guide for Everyday Investors

Published

on

Steps to Take Before Investing in Oil and Gas

Investing in the oil and gas industry can be a lucrative opportunity. However, for everyday investors, it’s essential to approach this sector with careful planning and education so you can make informed decisions. One effective way to gain this knowledge is by attending a Phoenix Capital Group webinar, where experts break down complex industry concepts. Below, we take a look at critical steps you can take before investing, whether you’re a seasoned investor or new to oil and gas investments.

1. Conduct Thorough Research on the Oil and Gas Industry

The first step to any investment is understanding the asset in which you’re investing. Instead of navigating this market directly, many novice investors choose corporate bonds from companies such as Phoenix Capital Group or index funds. It’s important to distinguish between direct investments in oil commodities, which are highly susceptible to price fluctuations, and vehicles like bonds that are issued by companies operating in the sector. Corporate bonds can offer more consistent returns but still require a thorough understanding of the risks involved.

2. Understand Your Investment Objectives

Before investing in any asset, make sure you can define your investment objectives clearly. Ask yourself what you hope to achieve by investing in oil and gas. Is it income generation, diversification, or the potential for long-term growth? Make sure your goals align with the investment’s profile. Defining your objectives will help you choose the right kind of oil and gas investment and ensure that it fits within your overall financial plan. For example, if you are looking for income generation, you might be better served to select a corporate bond with fixed returns that fits your risk profile.

3. Conduct Thorough Due Diligence

After you’ve established your investment objectives, the next step is due diligence. This involves thoroughly researching the companies and investment opportunities within the oil and gas sector. Make sure you review their track record, financial stability, and overall business model. As explained in Phoenix Capital Group webinar sessions, understanding a company’s strategy, risk management approach, and how they plan to generate returns is critical to making an informed investment decision.

For example, some companies focus on acquiring and managing oil and gas properties, concentrating on assets that are either currently producing or have the potential to produce oil in the future. Others might be focused on collecting royalties or participating in joint ventures. Understanding their approach to risk management and how they plan to generate returns is essential. By taking the time to research, you can make an informed decision rather than entering an investment without the necessary industry knowledge.

4. Leverage Educational Resources, Like Webinars

Investing in an industry as technical as oil and gas requires a basic understanding of how it works. This is why we recommend taking advantage of educational resources, like attending a Phoenix Capital Group webinar. These investor focused webinars are short, conveniently scheduled, and feature experts in the field who can break down complex concepts into easy-to-understand concepts. Whether you’re looking to diversify your portfolio or explore new investment avenues, these webinars provide the knowledge base necessary to make informed and strategic decisions.

5. Evaluate the Company’s Financial Health and Transparency

Transparency and financial stability are key factors in evaluating any investment. Look for companies that provide regular updates on their financial performance, project milestones, and operational details. Openness surrounding financial health and strategic direction demonstrates a commitment to building trust with investors. Transparency efforts should include detailed financial reports, disclosures on revenue streams, and insights into any risks or challenges the company faces.

6. Diversify Your Portfolio

Diversification is a cardinal rule of investing. Spreading your exposure across different asset classes can help mitigate the risk associated with the inherent volatility in the oil and gas market. Consider balancing your portfolio with other types of investments, such as bonds, real estate, or technology stocks, to provide a cushion in case one sector underperforms.

Conclusion

Investing in the oil and gas sector offers the potential for significant returns, but it also requires careful consideration and thorough preparation. By following the six steps outlined in this guide, you can make more informed decisions and better navigate the complexities of this volatile industry. Whether you choose to invest directly in oil commodities or through corporate bonds like those offered by Phoenix Capital Group, these steps will help you align your investment choices with your financial goals and risk tolerance. For further insights, consider attending a Phoenix Capital Group webinar, where you can deepen your understanding and refine your investment strategy.

Continue Reading

Recommended

The Importance of Professional Pressure Washing Services

Published

on

The Importance of Professional Pressure Washing Services

In the fast-paced world of property maintenance, the value of professional pressure washing services can’t be overstated. From residential homes to commercial buildings, maintaining external cleanliness not only enhances curb appeal but also extends the lifespan of building materials.

Residential Pressure Washing:

Homeowners benefit greatly from regular pressure washing, which removes harmful contaminants like mold, mildew, and algae. This not only prevents potential health hazards but also safeguards the home’s exterior from premature decay.

Commercial Pressure Washing:

For businesses, the external appearance can directly influence customer perception. Regular cleaning of sidewalks, parking lots, and facades keeps a business looking inviting and professional, which is essential for attracting and retaining customers.

Roof and Deck Cleaning:

These areas are particularly susceptible to the accumulation of dirt and organic growth, which can cause significant damage if not addressed. Professional cleaning helps prevent decay and leakage, prolonging the integrity and aesthetics of roofs and decks.

By investing in professional pressure washing services, property owners can maintain their premises in pristine condition, ultimately saving on costly repairs and replacements while ensuring their property looks its best year-round.

 

Continue Reading

Trending